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Carpal tunnel biopsy is a test in which a small piece of tissue is removed from the carpal tunnel (part of the wrist).
Biopsy - carpal tunnel
The skin of your wrist is scrubbed and injected with medicine that numbs the area. Through a small cut, a sample of tissue is removed from the carpal tunnel. This is done by direct removal of tissue or by needle aspiration.
Sometimes this procedure is performed at the time of carpal tunnel release.
Your doctor or nurse may ask that you not eat anything for a few hours before the test.
You may feel some stinging or burning when the numbing medicine is injected. You may also feel some pressure or tugging during the procedure. Afterward, the area may be tender or sore for a few days.
This test is usually done to see if you have a condition called amyloidosis. It is not usually done to diagnose carpal tunnel syndrome.
No abnormal tissues are found.
An abnormal result is a sign of amyloidosis.
If the carpal tunnel biopsy reveals a problem, your health care provider may suggest a carpal tunnel release procedure. Additional surgery to correct or improve the problem may be recommended.
Gertz MA. Amyloidosis. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011: chap 194.
LeBlanc KE, Cestia W. Carpal Tunnel Syndrome. Am Fam Physician. 2011;83(8):952-958.